Peripheral ossifying fibroma (POF) is a solitary gingival growth that is classified as a reactive hyperplastic inflammatory
lesion, although some authors suggest that it is a true benign neoplastic process. POF is thought to arise from the periodontal ligament.
This gingival growth can be misdiagnosed as a pyogenic granuloma, peripheral giant cell granuloma or some odontogenic tumors.
Only the histopathological examination permits to establish an accurate diagnosis. Pyogenic granuloma is very common in orthodontic
practice and, due to the tendency to relapse of the POF, the differential diagnosis is very important. Proper excision and curettage
of the adjacent tissues are necessary for prevention of recurrence. This article presents one case of POF which appeared and was
surgically excised during the orthodontic treatment of a 13 year old patient. The clinical and histopathological images of POF
and granuloma pyogenic and peripheral giant cell granuloma are compared and discussed.
(Rev Esp Ortod. 2009;39(1):039-045)